Advancing Novel Therapies
in Neuropsychiatry
for patients who have not found effective solutions for their disease

Clexio is a clinical-stage company designing novel drugs based on validated Mechanisms
of Action in NeuroPsychiatry

We are developing innovative therapies to address patients’ unmet needs in Major Depressive Disorder, Schizophrenia and Bipolar Depression.

Our lead drug candidate (CLE-100) is currently being tested in Phase 2 multicenter studies in the United States.

Our lead preclinical candidate (CLE-905) has recently completed IND enabling activities, with First-In-Human Phase 1 study expected to start in the coming months.

Our multidisciplinary team brings years of experience in the Pharmaceutical and Biotech industries and encompasses end-to-end drug development expertise, from early stage to advanced clinical stages, and regulatory approvals.

Individually and as a team, we are excited every day to use our expertise to innovate, integrate, apply, and develop new and effective solutions for people affected by mental health disorders.

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A multi-asset pipeline

We are a multi-asset company with a rich and growing pipeline, from preclinical to Phase 2 development stages.

Program
Pre clinical
Phase 1
Phase 2
Phase 3

CLE-905
M1/M4 muscarinic
agonist

CLE-901
Novel NMDA
antagonist

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CLE-100

NMDA antagonist

Developing a new treatment paradigm for patients suffering from Major Depressive Disorder

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CLE-905

M1/M4 muscarinic agonist

Developing a potent M1/M4 preferential muscarinic agonist for Schizophrenia

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CLE-901

Novel NMDA antagonist

Developing a novel NMDA antagonist for Bipolar Depression

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